Digital Measures Lead

At Roche you can show up as yourself, embraced for the unique qualities you bring. Our culture encourages personal expression, open dialogue, and genuine connections, where you are valued, accepted and respected for who you are, allowing you to thrive both personally and professionally. This is how we aim to prevent, stop and cure diseases and ensure everyone has access to healthcare today and for generations to come. Join Roche, where every voice matters.

The Position

In Roche’s Pharmaceutical Research and Early Development organization (pRED), we make transformative medicines for patients in order to tackle some of the world’s toughest unmet healthcare needs. At pRED, we are united by our mission to transform science into medicines. Together, we create a culture defined by curiosity, responsibility and humility, where our talented people are empowered and inspired to bring forward extraordinary life-changing innovation at speed.

The Computational Sciences Centre of Excellence (CoE) is a global organisation enabling Roche’s Research and Early Development units (pRED and gRED) to become more data-driven, more digitally adept, and better prepared for the challenges of the future. Within the CoE, Computational Medicine focuses on developing and applying innovative data analysis solutions to support clinical development — furthering our understanding of disease, disease progression, and individual patient response to treatment. In partnership with our scientists across pRED and gRED, we create better medicines by augmenting every part of R&D through our data-driven culture.

As Digital Measures Lead, you will play a pivotal role in embedding sensor-based digital health technologies into the heart of our pRED and gRED drug development programs. In disease areas like Alzheimer’s disease and Multiple Sclerosis, you will be responsible for shaping and executing on strategies that allow us to increase R&D productivity using digital clinical outcome assessments, digital biomarkers and exploratory digital measures collected from wearables, smartphones and other sensor-based digital health technologies (DHTs). You will be part of a team of experts located in Basel and South San Francisco and report to the Sensor Data Insights group lead in the Computational Biology and Medicine department.

The Opportunity:

• Partner with drug development teams to shape high-impact opportunities that drive clinical trial productivity improvements with sensor-based DHTs; embed them into disease area, clinical development, and biomarker strategies
• Develop comprehensive roadmaps to realize these opportunities, including assessing unmet measurement needs; evaluating, developing, validating sensor-based DHTs; driving towards community and regulatory acceptance
• Lead the delivery of these roadmaps. This includes securing governance endorsement and resourcing; leading CoE matrix team delivery; managing vendor/technology partnerships; ensuring seamless integration of sensor-based DHTs into clinical trials, including study designs, operations, data analyses; supporting results interpretation
• Foster external partnerships with industry, technology providers, academic centers, regulators, and patients to strengthen and accelerate these efforts
• Drive scientific communication and thought leadership both within and outside Roche through conferences and peer-reviewed publications, while upholding scientific rigor and patient-centricity in all activities

Who You Are:

• You hold a Ph.D. or equivalent experience in Digital Health, Life Sciences, Computer Science, Neuroscience or a related discipline coupled with at least 5+ years of professional experience leveraging sensor-based DHTs to improve R&D productivity in Phase I-IV trials
• You possess deep expertise in neuroscience, including Alzheimer's disease and Multiple Sclerosis, and understand how sensor-based DHTs can be applie